Alienation and loneliness is poison to our soul. It is a recurring motif in "Of Mice and Men" by John Steinbeck. Many characters in the novel experience alienation and loneliness because of their disabilities, gender, and their skin colour. By experiencing alienation and loneliness, the characters in the novel are emotionally hurt. Their behavior changes and they become different people. Alienation and loneliness changes humans for the worse and destroys us.
“The most terrible poverty is loneliness, and the feeling of being unloved.” - Mother Teresa of Calcutta
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